Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.53 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.53 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.35 |
| ▸ | FEN1 | P39748 | 2/20 | 0.35 |
| ▸ | MET | P08581 | 9/20 | 0.34 |
| ▸ | KDR | P35968 | 4/20 | 0.34 |
| ▸ | BRAF | P15056 | 1/20 | 0.34 |
| ▸ | RAF1 | P04049 | 5/20 | 0.34 |
| ▸ | MAP2K1 | Q02750 | 5/20 | 0.34 |
| ▸ | AXL | P30530 | 3/20 | 0.33 |
| ▸ | MST1R | Q04912 | 2/20 | 0.33 |
| ▸ | TYRO3 | Q06418 | 2/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.33 |
| ▸ | FLT4 | P35916 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31361325 | 1.00 | CYP3A4 (0.53) | CYP3A4CYP2D6FGFR1CYP2C9FGFR2 | |
| SCHEMBL31361281 | 0.92 | CYP3A4 (0.62) | CYP3A4CYP2D6FGFR1CYP2C9FGFR2 | |
| SCHEMBL31264666 | 0.87 | FGFR1 (0.70) | CYP3A4CYP2D6FGFR1CYP2C9FGFR2 | |
| SCHEMBL31361271 | 0.87 | FGFR1 (0.60) | CYP3A4CYP2D6FGFR1CYP2C9FGFR2 | |
| SCHEMBL31264657 | 0.82 | FGFR1 (0.70) | CYP3A4CYP2D6FGFR1CYP2C9FGFR2 | |
| SCHEMBL31264665 | 0.81 | FGFR1 (0.73) | CYP3A4CYP2D6FGFR1CYP2C9FGFR2 | |
| SCHEMBL31264706 | 0.81 | FGFR1 (0.72) | CYP3A4CYP2D6FGFR1CYP2C9FGFR2 | |
| SCHEMBL31264652 | 0.80 | FGFR1 (0.69) | CYP3A4CYP2D6FGFR1CYP2C9FGFR2 | |
| SCHEMBL30325695 | 0.79 | CYP3A4 (0.62) | CYP3A4CYP2D6FGFR1CYP2C9FGFR2 | |
| SCHEMBL31264714 | 0.79 | FGFR1 (0.69) | CYP3A4CYP2D6FGFR1CYP2C9FGFR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119161346-A | Pyrrolo-ring compound and application thereof in medicine | 康百达（四川）生物医药科技有限公司 | 2024-12-20 | — | — | CN | disclosed |