Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 20/20 | 0.47 |
| ▸ | PTGER2 | P43116 | 4/20 | 0.44 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.41 |
| ▸ | PTGER3 | P43115 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3673949 | 0.79 | PTGER4 (0.47) | PTGER4PTGER2PTGER1PTGER3 | |
| SCHEMBL3674055 | 0.79 | PTGER4 (0.45) | PTGER4PTGER2PTGER1PTGER3 | |
| SCHEMBL3679934 | 0.77 | PTGER4 (0.46) | PTGER4PTGER2PTGER1PTGER3 | |
| SCHEMBL1378976 | 0.76 | PTGER4 (0.70) | PTGER4PTGER2PTGER3 | |
| SCHEMBL1378979 | 0.76 | PTGER4 (0.70) | PTGER4PTGER2PTGER3 | |
| SCHEMBL1378974 | 0.76 | PTGER4 (0.70) | PTGER4PTGER2PTGER3 | |
| SCHEMBL1378982 | 0.76 | PTGER4 (0.70) | PTGER4PTGER2PTGER3 | |
| SCHEMBL2210033 | 0.76 | PTGER4 (0.62) | PTGER4PTGER2PTGER1PTGER3 | |
| SCHEMBL2210027 | 0.76 | PTGER4 (0.62) | PTGER4PTGER2PTGER1PTGER3 | |
| SCHEMBL1381087 | 0.74 | PTGER4 (0.51) | PTGER4PTGER2PTGER1PTGER3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1613621-B1 | PROSTAGLANDIN ANALOGS AS EP4 RECEPTOR AGONISTS | MERCK FROSST CANADA LTD (CA) | 2010-07-21 | — | — | EP | claimed |