Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 9/20 | 0.62 |
| ▸ | DDB1 | Q16531 | 6/20 | 0.62 |
| ▸ | CA2 | P00918 | 2/20 | 0.61 |
| ▸ | STAT3 | P40763 | 4/20 | 0.60 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.54 |
| ▸ | NCOR2 | Q9Y618 | 3/20 | 0.54 |
| ▸ | IDO1 | P14902 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL31361511 | 0.99 | CRBN (0.62) | CRBNDDB1CA2STAT3DYRK2 | |
| Trifluoroacetic Acid SCHEMBL23702559 | 0.99 | CRBN (0.62) | CRBNDDB1CA2STAT3DYRK2 | |
| Trifluoroacetic Acid SCHEMBL19747847 | 0.99 | CRBN (0.62) | CRBNDDB1CA2STAT3DYRK2 | |
| Trifluoroacetic Acid SCHEMBL23702525 | 0.99 | CRBN (0.62) | CRBNDDB1CA2STAT3DYRK2 | |
| Trifluoroacetic Acid SCHEMBL29546227 | 0.93 | CRBN (0.67) | CRBNDDB1CA2STAT3DYRK2 | |
| SCHEMBL29400212 | 0.92 | CRBN (0.66) | CRBNDDB1CA2STAT3DYRK2 | |
| SCHEMBL23974724 | 0.92 | CRBN (0.66) | CRBNDDB1CA2STAT3DYRK2 | |
| SCHEMBL19451305 | 0.92 | CRBN (0.66) | CRBNDDB1CA2STAT3DYRK2 | |
| Trifluoroacetic Acid SCHEMBL31371862 | 0.92 | CRBN (0.62) | CRBNDDB1CA2STAT3DYRK2 | |
| Trifluoroacetic Acid SCHEMBL17873751 | 0.92 | CRBN (0.66) | CRBNDDB1CA2STAT3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4746882-A1 | INHIBITORS OF SMNDC1 AND THEIR THERAPEUTIC USE | CeMM - Forschungszentrum für Molekulare Medizin GmbH (AT) | 2026-05-27 | — | — | EP | disclosed |
| WO-2025017207-A1 | INHIBITORS OF SMNDC1 AND THEIR THERAPEUTIC USE | CEMM - FORSCHUNGSZENTRUM FÜR MOLEKULARE MEDIZIN GMBH (AT) | 2025-01-23 | — | — | WO | disclosed |