Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT4 | P35916 | 7/20 | 0.47 |
| ▸ | KDR | P35968 | 6/20 | 0.47 |
| ▸ | JAK3 | P52333 | 7/20 | 0.46 |
| ▸ | JAK2 | O60674 | 6/20 | 0.46 |
| ▸ | JAK1 | P23458 | 6/20 | 0.46 |
| ▸ | TYK2 | P29597 | 1/20 | 0.44 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.43 |
| ▸ | IGF1R | P08069 | 2/20 | 0.42 |
| ▸ | MELK | Q14680 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31361736 | 0.89 | JAK3 (0.50) | FLT4KDRJAK3JAK2JAK1 | |
| SCHEMBL31361564 | 0.89 | JAK3 (0.53) | FLT4KDRJAK3JAK2JAK1 | |
| SCHEMBL31361637 | 0.85 | FLT4 (0.50) | FLT4KDRJAK3JAK2JAK1 | |
| SCHEMBL31454767 | 0.85 | FLT4 (0.54) | FLT4KDRJAK3JAK2JAK1 | |
| SCHEMBL31361634 | 0.84 | JAK3 (0.59) | FLT4KDRJAK3JAK2JAK1 | |
| SCHEMBL31361622 | 0.83 | JAK3 (0.51) | FLT4KDRJAK3JAK2JAK1 | |
| SCHEMBL31361614 | 0.83 | JAK1 (0.51) | FLT4KDRJAK3JAK2JAK1 | |
| SCHEMBL31361728 | 0.83 | JAK3 (0.51) | FLT4KDRJAK3JAK2JAK1 | |
| SCHEMBL31361592 | 0.82 | JAK3 (0.52) | FLT4KDRJAK3JAK2JAK1 | |
| SCHEMBL30962648 | 0.82 | JAK3 (0.54) | FLT4KDRJAK3JAK2JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025017116-A1 | PHARMACEUTICAL COMPOUNDS HAVING ACTIVITY AS WEE1 INHIBITORS | SENTINEL ONCOLOGY LIMITED (GB) | 2025-01-23 | — | — | WO | disclosed |