Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 11/20 | 0.47 |
| ▸ | JAK1 | P23458 | 10/20 | 0.47 |
| ▸ | JAK2 | O60674 | 10/20 | 0.47 |
| ▸ | TYK2 | P29597 | 4/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.43 |
| ▸ | CDK9 | P50750 | 4/20 | 0.41 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.40 |
| ▸ | TNK2 | Q07912 | 2/20 | 0.39 |
| ▸ | HCK | P08631 | 1/20 | 0.38 |
| ▸ | BTK | Q06187 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31361596 | 1.00 | JAK3 (0.47) | JAK3JAK1JAK2TYK2HDAC3 | |
| SCHEMBL31361705 | 1.00 | JAK3 (0.47) | JAK3JAK1JAK2TYK2HDAC3 | |
| SCHEMBL31361723 | 1.00 | JAK3 (0.47) | JAK3JAK1JAK2TYK2HDAC3 | |
| SCHEMBL31361679 | 0.86 | JAK1 (0.54) | JAK3JAK1JAK2TYK2HDAC3 | |
| SCHEMBL31361564 | 0.86 | JAK3 (0.53) | JAK3JAK1JAK2TYK2MAP3K7 | |
| SCHEMBL31361614 | 0.86 | JAK1 (0.51) | JAK3JAK1JAK2TYK2HDAC3 | |
| SCHEMBL31361719 | 0.86 | JAK3 (0.61) | JAK3JAK1JAK2TYK2MAP3K7 | |
| SCHEMBL31361590 | 0.86 | JAK3 (0.44) | JAK3JAK1JAK2TYK2HDAC3 | |
| SCHEMBL31361612 | 0.86 | JAK3 (0.44) | JAK3JAK1JAK2TYK2HDAC3 | |
| SCHEMBL31361637 | 0.85 | FLT4 (0.50) | JAK3JAK1JAK2TYK2MAP3K7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025017116-A1 | PHARMACEUTICAL COMPOUNDS HAVING ACTIVITY AS WEE1 INHIBITORS | SENTINEL ONCOLOGY LIMITED (GB) | 2025-01-23 | — | — | WO | disclosed |