SCHEMBL3136238

SCHEMBL3136238

ClCl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL124 1.00
SCHEMBL1796550 1.00
SCHEMBL1225018 0.82
SCHEMBL629993 0.82
SCHEMBL11846659 0.82
SCHEMBL11211442 0.82
SCHEMBL11405620 0.82
SCHEMBL5399196 0.82
SCHEMBL11577965 0.82
SCHEMBL11080219 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120142731-A1 METHODS OF INHIBITING VIRAL INFECTION FUNCTIONAL GENETICS, INC. (US) 2012-06-07 US claimed
EP-2203065-A2 METHODS OF INHIBITING VIRAL INFECTION Functional Genetics, Inc. (US) 2010-07-07 EP claimed
WO-2009091435-A2 METHODS OF INHIBITING VIRAL INFECTION FUNCTIONAL GENETICS, INC. (US) 2009-07-23 WO claimed
US-RE38524-E1 Dipeptide derivatives as growth hormone secretagogues PFIZER INC. 2004-06-01 US claimed
US-11873307-B2 Manufacture of compounds and compositions for inhibiting the activity of SHP2 NOVARTIS AG (CH) 2024-01-16 US disclosed
EP-4074703-B1 PYRIDINYL-(AZA)INDOLSULFONAMIDES UCB PHARMA GMBH (DE) 2023-11-29 EP disclosed
US-20210355134-A1 MANUFACTURE OF COMPOUNDS AND COMPOSITIONS FOR INHIBITING THE ACTIVITY OF SHP2 NOVARTIS AG (CH) 2021-11-18 US disclosed
EP-3856744-A1 MANUFACTURE OF COMPOUNDS AND COMPOSITIONS FOR INHIBITING THE ACTIVITY OF SHP2 Novartis AG (CH) 2021-08-04 EP disclosed
WO-2020065452-A1 MANUFACTURE OF COMPOUNDS AND COMPOSITIONS FOR INHIBITING THE ACTIVITY OF SHP2 NOVARTIS AG (CH) 2020-04-02 WO disclosed
CN-103282358-A Cyp11b, cyp17, and/or cyp21 inhibitors BIOMARIN PHARM INC 2013-09-04 CN disclosed
US-20040077654-A1 Aryl piperidine and piperazine derivatives as inducers of ldl-receptor expression SMITHKLINE BEECHAM CORPORATION 2004-04-22 US disclosed
EP-1351936-A1 ARYL PIPERIDINE AND PIPERAZINE DERIVATIVES AS INDUCERS OF LDL-RECEPTOR EXPRESSION GLAXO GROUP LIMITED (GB) 2003-10-15 EP disclosed
US-5629168-A Chemiluminescent enhancers BRITISH TECHNOLOGY GROUP LIMITED (GB) 1997-05-13 US disclosed
US-5079347-A Fiber reactive dyes for wool and cellulose HOECHST AKTIENGESELLSCHAFT (DE) 1992-01-07 US disclosed
US-4694005-A CARDIOTONIC, HYPOTENSIVE IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1987-09-15 US disclosed
US-4584298-A CARDIOTONIC AGENTS, HYPOTENSIVE AGENTS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1986-04-22 US disclosed
US-4539130-A SULFONATE AND CARBOXYLIC ACID ESTERS, ANHYDRIDES AND IMIDE DERIVATIVES THE PROCTER & GAMBLE COMPANY (US) 1985-09-03 US disclosed
US-4495185-A CARDIOTONIC AND/OR HYPOTENSIVE AGENTS IMPERIAL CHEMICAL INDUSTRIES, PLC (GB) 1985-01-22 US disclosed
US-4489074-A CARDIOTONIC AGENTS, HYPOTENSIVE AGENTS IMPERIAL CHEMICAL INDUSTRIES, PLC (GB) 1984-12-18 US disclosed
US-3930671-A Color former and pressure-sensitive copying paper FUJI PHOTO FILM CO., LTD. (JA) 1976-01-06 US disclosed