Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC1 | P33527 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 5/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | GUSB | P08236 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4164088 | 0.84 | ABCC1 (0.38) | ABCC1NPC1RAB9AHPGDTDP1 | |
| SCHEMBL4164473 | 0.79 | NAMPT (0.41) | ALDH1A1KDM4ENPC1HPGDTDP1 | |
| SCHEMBL14134217 | 0.78 | MAPT (0.44) | ABCC1ALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL7013954 | 0.77 | ABCC1 (0.42) | ABCC1ALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL29956709 | 0.77 | ABCC1 (0.42) | ABCC1ALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL14052434 | 0.74 | PTGS1 (0.48) | ABCC1ALDH1A1RAB9AHPGDMAPT | |
| SCHEMBL25412667 | 0.73 | NAMPT (0.45) | ALDH1A1KDM4ENPC1RAB9AHPGD | |
| SCHEMBL15853778 | 0.73 | CLK1 (0.38) | ALDH1A1KDM4ENPC1RAB9AHPGD | |
| SCHEMBL8700238 | 0.72 | HPGD (0.44) | ALDH1A1NPC1RAB9AHPGDTDP1 | |
| SCHEMBL1844052 | 0.72 | TSHR (0.57) | ALDH1A1KDM4ENPC1RAB9AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025034858-A1 | FUSED PYRIDINES FOR THE TREATMENT OF CANCER AND OTHER INDICATIONS | THERAS, INC. (US) | 2025-02-13 | — | — | WO | disclosed |