Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 9/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | VDR | P11473 | 1/20 | 0.38 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25352929 | 1.00 | BRD4 (0.44) | BRD4CYP2D6CYP1A2MMP2ALDH1A1 | |
| SCHEMBL10756668 | 1.00 | BRD4 (0.44) | BRD4CYP2D6CYP1A2MMP2ALDH1A1 | |
| SCHEMBL10757005 | 0.89 | BRD4 (0.40) | BRD4CYP2D6CYP1A2ALDH1A1MAPT | |
| SCHEMBL31371773 | 0.86 | CYP2D6 (0.44) | CYP2D6CYP1A2MMP2ALDH1A1CYP3A4 | |
| SCHEMBL31309741 | 0.86 | CYP2D6 (0.42) | CYP2D6CYP1A2MMP2ALDH1A1CYP3A4 | |
| SCHEMBL31624936 | 0.83 | CYP2D6 (0.43) | CYP2D6CYP1A2MMP2ALDH1A1CYP3A4 | |
| SCHEMBL31754953 | 0.83 | CYP2D6 (0.35) | BRD4CYP2D6CYP1A2MMP2ALDH1A1 | |
| SCHEMBL31754923 | 0.81 | CYP2D6 (0.34) | BRD4CYP2D6CYP1A2ALDH1A1CYP3A4 | |
| SCHEMBL19950674 | 0.80 | CYP2D6 (0.43) | CYP2D6CYP1A2MMP2ALDH1A1CYP3A4 | |
| SCHEMBL4835733 | 0.80 | CYP2D6 (0.43) | CYP2D6CYP1A2MMP2ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025034858-A1 | FUSED PYRIDINES FOR THE TREATMENT OF CANCER AND OTHER INDICATIONS | THERAS, INC. (US) | 2025-02-13 | — | — | WO | disclosed |