Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.34 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4346843 | 0.86 | SPHK1 (0.40) | SPHK1BRD4MMP13MEN1KMT2A | |
| SCHEMBL2669188 | 0.86 | SPHK1 (0.40) | SPHK1BRD4MMP13MEN1KMT2A | |
| SCHEMBL4346836 | 0.86 | SPHK1 (0.40) | SPHK1BRD4MMP13MEN1KMT2A | |
| SCHEMBL2332163 | 0.85 | SPHK1 (0.35) | SPHK1BRD4MMP13MEN1KMT2A | |
| SCHEMBL8240970 | 0.85 | SPHK1 (0.33) | SPHK1BRD4MMP13MEN1KMT2A | |
| SCHEMBL2322323 | 0.85 | ABCG2 (0.34) | SPHK1BRD4MMP13MEN1KMT2A | |
| SCHEMBL2332152 | 0.85 | SPHK1 (0.35) | SPHK1BRD4MMP13MEN1KMT2A | |
| SCHEMBL2322332 | 0.85 | ABCG2 (0.34) | SPHK1BRD4MMP13MEN1KMT2A | |
| SCHEMBL2332146 | 0.85 | SPHK1 (0.35) | SPHK1BRD4MMP13MEN1KMT2A | |
| SCHEMBL2322328 | 0.85 | ABCG2 (0.34) | SPHK1BRD4MMP13MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250066328-A1 | PARP7 INHIBITORS | GILEAD SCIENCES, INC. | 2025-02-27 | — | — | US | disclosed |
| WO-2025024663-A1 | PARP7 INHIBITORS | GILEAD SCIENCES, INC. (US) | 2025-01-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250066328-A1 | PARP7 INHIBITORS | PARP1, PARP2, PARP8 | SPHK1 2346/4885BRD4 345/4885MMP13 2122/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.