Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PABPC1 | P11940 | 4/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8349276 | 0.80 | KMT2A (0.53) | KMT2AMEN1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL27787981 | 0.80 | KMT2A (0.40) | KMT2AMEN1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL27954500 | 0.77 | KMT2A (0.59) | KMT2AMEN1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL6269870 | 0.77 | KMT2A (0.55) | KMT2AMEN1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL12933403 | 0.77 | KMT2A (0.50) | KMT2AMEN1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL30119647 | 0.77 | CA12 (0.43) | MAPTTSHRNPSR1SLC22A12 | |
| SCHEMBL82717 | 0.77 | CA12 (0.43) | MAPTTSHRNPSR1SLC22A12 | |
| SCHEMBL8348534 | 0.76 | KMT2A (0.49) | KMT2AMEN1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL4574251 | 0.76 | KMT2A (0.53) | KMT2AMEN1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL29636514 | 0.75 | KMT2A (0.55) | KMT2AMEN1KDM4EMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059074-A1 | BICYCLIC COMPOUNDS FOR RESTORING MUTANT P53 FUNCTION | PMV PHARMACEUTICALS, INC. (US) | 2025-03-20 | — | — | WO | disclosed |