Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 9/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30954981 | 0.84 | NR1H2 (0.42) | NR1H2USP2SMN1; SMN2RORCHPGD | |
| SCHEMBL31722107 | 0.84 | NR1H2 (0.42) | NR1H2USP2SMN1; SMN2RORCHPGD | |
| SCHEMBL21597767 | 0.84 | NR1H2 (0.42) | NR1H2USP2SMN1; SMN2RORCHPGD | |
| SCHEMBL15719645 | 0.84 | NR1H2 (0.42) | NR1H2USP2SMN1; SMN2RORCHPGD | |
| SCHEMBL17630365 | 0.83 | NR1H2 (0.41) | NR1H2USP2SMN1; SMN2RORCPIK3CD | |
| SCHEMBL16224509 | 0.83 | NR1H2 (0.43) | NR1H2USP2SMN1; SMN2RORCHPGD | |
| SCHEMBL23177361 | 0.81 | NR1H2 (0.42) | NR1H2USP2SMN1; SMN2RORCPIK3CD | |
| SCHEMBL28736710 | 0.81 | NR1H2 (0.42) | NR1H2USP2SMN1; SMN2RORCPIK3CD | |
| SCHEMBL16714648 | 0.80 | NR1H2 (0.43) | NR1H2USP2SMN1; SMN2RORCHPGD | |
| SCHEMBL17499855 | 0.80 | NR1H2 (0.43) | NR1H2USP2SMN1; SMN2RORCHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059074-A1 | BICYCLIC COMPOUNDS FOR RESTORING MUTANT P53 FUNCTION | PMV PHARMACEUTICALS, INC. (US) | 2025-03-20 | — | — | WO | disclosed |