Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 4/20 | 0.46 |
| ▸ | LCK | P06239 | 3/20 | 0.43 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.36 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.34 |
| ▸ | TUBB | P07437 | 1/20 | 0.34 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.34 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.34 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.34 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.34 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.34 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.34 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.34 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18554539 | 1.00 | DHODH (0.46) | DHODHLCKCACNA1HCACNA1BCACNA1C | |
| SCHEMBL20378076 | 0.89 | ATR (0.43) | DHODHLCKCACNA1HCACNA1BCACNA1C | |
| SCHEMBL30138958 | 0.89 | ATR (0.43) | DHODHLCKCACNA1HCACNA1BCACNA1C | |
| SCHEMBL31363742 | 0.79 | PARP1 (0.44) | LCK | |
| SCHEMBL6582251 | 0.76 | LCK (0.45) | LCKCACNA1HCACNA1BCACNA1CBCHE | |
| SCHEMBL6584685 | 0.74 | LCK (0.50) | LCKCACNA1HCACNA1BCACNA1CBCHE | |
| SCHEMBL31370470 | 0.74 | LCK (0.53) | LCKBCHETUBB4ATUBBTUBA3C | |
| SCHEMBL20482409 | 0.72 | DHODH (0.61) | DHODH | |
| SCHEMBL6784411 | 0.71 | LCK (0.57) | LCKBCHEHSD17B10TUBB4ATUBB | |
| SCHEMBL31721205 | 0.71 | LCK (0.69) | LCKTUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059074-A1 | BICYCLIC COMPOUNDS FOR RESTORING MUTANT P53 FUNCTION | PMV PHARMACEUTICALS, INC. (US) | 2025-03-20 | — | — | WO | disclosed |