Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | GRN | P28799 | 1/20 | 0.49 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | DHX9 | Q08211 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 2/20 | 0.39 |
| ▸ | RCOR1 | Q9UKL0 | 2/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3318854 | 0.81 | SMN1; SMN2 (0.60) | SMN1; SMN2LMNAHPGDGRNSORT1 | |
| SCHEMBL31534794 | 0.80 | CA12 (0.42) | SMN1; SMN2LMNAHPGDCA12CA1 | |
| SCHEMBL22993585 | 0.80 | SMN1; SMN2 (0.58) | SMN1; SMN2LMNAHPGDGRNSORT1 | |
| SCHEMBL1458487 | 0.80 | SMN1; SMN2 (0.62) | SMN1; SMN2LMNAHPGDGRNSORT1 | |
| SCHEMBL2828757 | 0.78 | SMN1; SMN2 (0.55) | SMN1; SMN2LMNAHPGDGRNSORT1 | |
| SCHEMBL23977122 | 0.76 | KDM1A (0.55) | SMN1; SMN2LMNAHPGDGRNSORT1 | |
| SCHEMBL27897764 | 0.76 | SMN1; SMN2 (0.55) | SMN1; SMN2LMNAHPGDGRNSORT1 | |
| SCHEMBL28767700 | 0.75 | SMN1; SMN2 (0.53) | SMN1; SMN2LMNAHPGDGRNSORT1 | |
| SCHEMBL15455083 | 0.75 | SMN1; SMN2 (0.56) | SMN1; SMN2LMNAHPGDGRNSORT1 | |
| SCHEMBL357320 | 0.75 | SMN1; SMN2 (0.53) | SMN1; SMN2LMNAHPGDGRNSORT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059074-A1 | BICYCLIC COMPOUNDS FOR RESTORING MUTANT P53 FUNCTION | PMV PHARMACEUTICALS, INC. (US) | 2025-03-20 | — | — | WO | disclosed |