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Acetyl Podocarpic Acid Anhydride

Acetyl Podocarpic Acid Anhydride

SCHEMBL31364127

CC(=O)Oc1ccc2c(c1)[C@@]1(C)CCC[C@](C)(C(=O)OC(=O)[C@@]3(C)CCC[C@]4(C)c5cc(OC(C)=O)ccc5CC[C@@H]34)[C@@H]1CC2

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ NR1H2 P55055 10/20 1.00
▸ NR1H3 Q13133 10/20 1.00
▸ POLA1 P09884 6/20 0.64
▸ SOD1 P00441 1/20 0.54
▸ CYP2C9 P11712 1/20 0.51
▸ TSHR P16473 1/20 0.51
▸ CYP2C19 P33261 1/20 0.51
▸ CYP3A4 P08684 1/20 0.51
▸ PDE4D Q08499 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetyl Podocarpic Acid Anhydride SCHEMBL5538089 1.00 NR1H2 (1.00) NR1H2NR1H3POLA1SOD1CYP2C9
SCHEMBL6312566 0.90 NR1H2 (0.82) NR1H2NR1H3POLA1CYP2C9TSHR
SCHEMBL6312574 0.90 NR1H2 (0.82) NR1H2NR1H3POLA1CYP2C9TSHR
SCHEMBL15591859 0.87 NR1H2 (0.76) NR1H2NR1H3POLA1SOD1CYP3A4
SCHEMBL14874213 0.85 NR1H2 (0.73) NR1H2NR1H3POLA1SOD1CYP2C9
SCHEMBL6312549 0.84 NR1H2 (0.72) NR1H2NR1H3POLA1SOD1CYP2C9
SCHEMBL6312546 0.84 NR1H2 (0.72) NR1H2NR1H3POLA1SOD1CYP2C9
SCHEMBL6312666 0.84 NR1H2 (1.00) NR1H2NR1H3POLA1SOD1
SCHEMBL20561396 0.84 NR1H2 (1.00) NR1H2NR1H3POLA1SOD1
SCHEMBL6312669 0.84 NR1H2 (1.00) NR1H2NR1H3POLA1SOD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025059405-A1 COMPOSITIONS FOR USE IN A METHOD OF TREATING A MOTOR NEURON DISEASE OR CONDITION ASSOCIATED WITH A SPG11 PATHOGENIC VARIANT THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2025-03-20 — — WO disclosed
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