Glycolic Acid

Glycolic Acid

SCHEMBL3136418

CSC(O)C(=O)O.O=C(O)CO

nearest known ligand 0.36

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Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
OR51E2 Q9H255 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
TP53 P04637 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
CYP2C9 P11712 1/20 0.34
TSHR P16473 1/20 0.34
RNPEP Q9H4A4 1/20 0.32
TET2 Q6N021 3/20 0.32
KDM4A O75164 2/20 0.32
KDM4C Q9H3R0 2/20 0.32
KDM2A Q9Y2K7 2/20 0.32
TET3 O43151 1/20 0.32
SLC22A6 Q4U2R8 1/20 0.32
FOLH1 Q04609 1/20 0.31
CYP1A2 P05177 1/20 0.31
FFAR3 O14843 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL61001 0.87
Hydrochloric Acid SCHEMBL21440339 0.84
SCHEMBL3266952 0.84
Benzene SCHEMBL27272546 0.81 TP53 (0.40) TP53TSHRRNPEP
SCHEMBL11542755 0.79 TP53 (0.38) TP53TSHRRNPEP
Mercaptopropionic Acid SCHEMBL28098369 0.78 ACE (0.41) TSHRTET2KDM4AKDM4CKDM2A
SCHEMBL1738977 0.77 TP53 (0.36) TP53TSHR
Glycolic Acid SCHEMBL28094374 0.76 OR51E2 (0.39) OR51E2TDP1TP53SMN1; SMN2CYP2C9
Lactic Acid SCHEMBL4261279 0.73 TP53 (0.69) OR51E2TP53SMN1; SMN2CYP2C9TSHR
Lactic Acid SCHEMBL424598 0.73 TP53 (0.69) OR51E2TP53SMN1; SMN2CYP2C9TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117486855-A Process for preparing 2, 5-thiophenedicarboxylic acid 三门峡奥科科技有限公司 2024-02-02 CN disclosed
US-7642371-B2 Process for preparing dialkyl thiodiglycolates SALTIGO GMBH (DE) 2010-01-05 US disclosed
US-20090163736-A1 PROCESS FOR PREPARING DIALKYL THIODIGLYCOLATES SALTIGO GMBH (DE) 2009-06-25 US disclosed
US-6313342-B1 Synthesis of esters of mercaptocarboxylic acids ELF ATOCHEM S.A. (FR) 2001-11-06 US disclosed
US-5773641-A REACTING A HYDROSULFIDE WITH THE CORRESPONDING HALOCARBOXYLIC ESTER ELF ATOCHEM S.A. (FR) 1998-06-30 US disclosed
EP-0249236-B1 N-1H-TETRAZOL-5-YL-(5-RING)-CARBOXAMIDE-DERIVATIVES, A PROCESS FOR THEIR MANUFACTURE, AND THE USE THEREOF WARNER-LAMBERT COMPANY (US) 1991-04-24 EP disclosed
US-4824958-A Process for the preparation of n-1H-tetrazol-5-yl-2-pyrrole carboxamides WARNER-LAMBERT COMPANY (US) 1989-04-25 US disclosed
US-4748183-A N-1H-tetrazol-5-yl-2-thiophene carboxamides, N-1H-tetrazol-5-yl-2-pyrrole carboxamides, N-1H-tetrazol-5-yl-2-furan carboxamides, and anti-allergic and anti-inflammatory use thereof WARNER-LAMBERT COMPANY (US) 1988-05-31 US disclosed
EP-0249236-A1 N-1H-Tetrazol-5-yl-(5-Ring)-carboxamide-derivatives, a process for their manufacture, and the use thereof WARNER-LAMBERT COMPANY (US) 1987-12-16 EP disclosed