Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.46 |
| ▸ | NQO2 | P16083 | 6/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | PRKDC | P78527 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CDC25A | P30304 | 1/20 | 0.40 |
| ▸ | CDC25B | P30305 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26607750 | 1.00 | KDM4E (0.50) | KDM4ETDP1MAPTBLMTNKS2 | |
| SCHEMBL6682269 | 0.82 | CA12 (0.48) | KDM4ETDP1MAPTBLM | |
| SCHEMBL19146396 | 0.81 | NQO2 (0.60) | KDM4ETDP1MAPTBLMTNKS2 | |
| SCHEMBL12669659 | 0.79 | NQO2 (0.43) | KDM4ETDP1MAPTBLMNQO2 | |
| SCHEMBL359043 | 0.77 | TDP1 (0.43) | KDM4ETDP1MAPTBLMALDH1A1 | |
| SCHEMBL30349806 | 0.76 | MAPT (0.52) | KDM4ETDP1MAPTBLMNQO2 | |
| SCHEMBL27944806 | 0.76 | GRIN2D (0.67) | TDP1MAPTBLMCYP3A4ALOX15 | |
| SCHEMBL26607699 | 0.75 | KDM4E (0.53) | KDM4EMAPTTNKS2NQO2CYP19A1 | |
| SCHEMBL16896940 | 0.75 | GRIN2D (0.57) | KDM4ETNKS2NQO2CYP19A1ALDH1A1 | |
| SCHEMBL3827659 | 0.73 | KDM4E (0.67) | KDM4ETDP1MAPTBLMNQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250382308-A1 | COMPOUNDS ACTIVE TOWARDS BROMODOMAINS | NUEVOLUTION AS (US) | 2025-12-18 | — | — | US | disclosed |
| CN-119365455-A | Having a bromodomain active compounds | 纽韦卢森公司 | 2025-01-24 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250382308-A1 | COMPOUNDS ACTIVE TOWARDS BROMODOMAINS | BRD4, BRD3, EP300 | KDM4E 438/4885TDP1 1713/4885MAPT 908/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.