SCHEMBL31365770

SCHEMBL31365770

CN1CCN(C(=O)C(CCCCO)NC(=O)c2ccc(C#N)cc2)CC1

nearest known ligand 0.64

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 20/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17984376 1.00 KDM1A (0.64) KDM1A
SCHEMBL17984258 0.87 KDM1A (0.60) KDM1A
SCHEMBL16455151 0.85 KDM1A (0.59) KDM1A
SCHEMBL26148130 0.85 KDM1A (0.59) KDM1A
SCHEMBL16447391 0.85 KDM1A (0.54) KDM1A
SCHEMBL16447393 0.85 KDM1A (0.54) KDM1A
SCHEMBL16455064 0.82 KDM1A (0.60) KDM1A
SCHEMBL18016097 0.81 KDM1A (0.65) KDM1A
SCHEMBL20546624 0.80 MEN1 (0.49) KDM1A
SCHEMBL17981439 0.80 MEN1 (0.49) KDM1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3256218-B1 A KDM1A INHIBITOR AND ITS USE IN THERAPY IMAGO BIOSCIENCES INC (US) 2024-12-11 EP disclosed