Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 8/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | MMP2 | P08253 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30035740 | 0.98 | EPHX1 (0.59) | EPHX1SMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL30034737 | 0.96 | EPHX1 (0.52) | EPHX1SMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL5263260 | 0.89 | EPHX1 (0.41) | EPHX1SMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL5263263 | 0.89 | EPHX1 (0.41) | EPHX1SMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL112091 | 0.82 | — | — | |
| SCHEMBL23573302 | 0.81 | EPHX1 (0.57) | EPHX1SMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL113152 | 0.80 | EPHX1 (0.50) | EPHX1HTTCA12CA1CA2 | |
| SCHEMBL1416705 | 0.80 | EPHX1 (0.50) | EPHX1HTTCA12CA1CA2 | |
| SCHEMBL28110614 | 0.80 | EPHX1 (0.50) | EPHX1HTTCA12CA1CA2 | |
| SCHEMBL1416449 | 0.80 | EPHX1 (0.50) | EPHX1HTTCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114945572-B | HBF pharmacological inducing compounds for the treatment of sickle cell anemia and beta-thalassemia | 周美吟 | 2025-01-28 | — | — | CN | disclosed |