Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 7/20 | 1.00 |
| ▸ | ESR1 | P03372 | 4/20 | 0.67 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.67 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.67 |
| ▸ | PDE2A | O00408 | 1/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | GLA | P06280 | 3/20 | 0.61 |
| ▸ | GAA | P10253 | 3/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | CASP1 | P29466 | 2/20 | 0.61 |
| ▸ | CASP7 | P55210 | 2/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | MAOB | P27338 | 2/20 | 0.61 |
| ▸ | CA12 | O43570 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL591899 | 1.00 | HSD17B3 (1.00) | HSD17B3ESR1ESR2ERAP1PDE2A | |
| SCHEMBL28446883 | 0.98 | HSD17B3 (0.96) | HSD17B3ESR1ESR2ERAP1PDE2A | |
| SCHEMBL10847031 | 0.92 | HSD17B3 (0.84) | HSD17B3ESR1ESR2ERAP1PDE2A | |
| SCHEMBL31312649 | 0.89 | HSD17B3 (0.80) | HSD17B3ESR1ESR2ERAP1PDE2A | |
| SCHEMBL5957207 | 0.89 | HSD17B3 (0.79) | HSD17B3ESR1ESR2ERAP1PDE2A | |
| SCHEMBL10846443 | 0.87 | HSD17B3 (0.77) | HSD17B3ESR1ESR2ERAP1PDE2A | |
| SCHEMBL10854362 | 0.87 | HSD17B3 (0.77) | HSD17B3ESR1ESR2ERAP1PDE2A | |
| SCHEMBL11116921 | 0.87 | HSD17B3 (0.77) | HSD17B3ESR1ESR2ERAP1PDE2A | |
| Trifluoromethanesulfonic Acid SCHEMBL10847174 | 0.86 | HSD17B3 (0.74) | HSD17B3ESR1ESR2ERAP1PDE2A | |
| SCHEMBL8848474 | 0.86 | HSD17B3 (0.77) | HSD17B3ESR1ESR2ERAP1PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119487021-A | Heterocyclic derivatives as inhibitors of mitogen-activated protein kinase (MEK) | 内斯特治疗公司 | 2025-02-18 | — | — | CN | disclosed |