Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 18/20 | 0.76 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.60 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.60 |
| ▸ | ESR2 | Q92731 | 8/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | PLD2 | O14939 | 1/20 | 0.58 |
| ▸ | KDM1A | O60341 | 1/20 | 0.58 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | C5 | P01031 | 1/20 | 0.58 |
| ▸ | FYN | P06241 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31367878 | 0.98 | ESR1 (0.76) | ESR1HDAC1HDAC6ESR2MEN1 | |
| SCHEMBL31367881 | 0.95 | ESR1 (0.79) | ESR1HDAC1HDAC6ESR2MEN1 | |
| SCHEMBL31367876 | 0.92 | ESR1 (0.74) | ESR1HDAC1HDAC6ESR2MEN1 | |
| SCHEMBL6976728 | 0.89 | ESR1 (0.81) | ESR1ESR2MEN1ALDH1A1LMNA | |
| SCHEMBL31367888 | 0.89 | ESR1 (0.72) | ESR1ESR2MEN1ALDH1A1LMNA | |
| SCHEMBL11550344 | 0.88 | ESR1 (0.82) | ESR1ESR2MEN1ALDH1A1LMNA | |
| SCHEMBL30898312 | 0.86 | ESR1 (0.84) | ESR1ESR2MEN1ALDH1A1LMNA | |
| SCHEMBL30898311 | 0.86 | ESR1 (0.84) | ESR1ESR2MEN1ALDH1A1LMNA | |
| SCHEMBL6969969 | 0.86 | ESR1 (0.84) | ESR1ESR2MEN1ALDH1A1LMNA | |
| SCHEMBL6969255 | 0.86 | ESR1 (0.84) | ESR1ESR2MEN1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119751438-A | 2- (4-Hydroxyphenyl) benzothiophene compound using methylene blue analogue as protein degradation product and application thereof | 贵州大学 | 2025-04-04 | — | — | CN | disclosed |
| CN-119371417-A | 2- (4-Hydroxyphenyl) benzothiophene compound using methylene blue analogue as protein degradation product and application thereof | 贵州大学 | 2025-01-28 | — | — | CN | disclosed |