Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 18/20 | 0.52 |
| ▸ | JAK1 | P23458 | 6/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.51 |
| ▸ | JAK2 | O60674 | 3/20 | 0.51 |
| ▸ | STAT3 | P40763 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28662538 | 1.00 | TYK2 (0.52) | TYK2JAK1KCNH2JAK2STAT3 | |
| SCHEMBL25670345 | 0.92 | TYK2 (0.52) | TYK2JAK1KCNH2JAK2STAT3 | |
| SCHEMBL30465864 | 0.92 | TYK2 (0.52) | TYK2JAK1KCNH2JAK2STAT3 | |
| SCHEMBL25748683 | 0.92 | TYK2 (0.52) | TYK2JAK1KCNH2JAK2STAT3 | |
| SCHEMBL29882968 | 0.91 | TYK2 (0.61) | TYK2JAK1KCNH2JAK2STAT3 | |
| SCHEMBL25750974 | 0.91 | TYK2 (0.61) | TYK2JAK1KCNH2JAK2STAT3 | |
| SCHEMBL27292496 | 0.88 | JAK2 (0.52) | TYK2JAK1KCNH2JAK2STAT3 | |
| SCHEMBL27199311 | 0.88 | TYK2 (0.63) | TYK2JAK1KCNH2JAK2STAT3 | |
| SCHEMBL30465823 | 0.88 | TYK2 (0.63) | TYK2JAK1KCNH2JAK2STAT3 | |
| SCHEMBL28647134 | 0.86 | TYK2 (0.48) | TYK2JAK1KCNH2JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113563309-B | Pyridine derivative and preparation method and application thereof | 浙江海正药业股份有限公司 | 2024-12-13 | — | — | CN | disclosed |