Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 18/20 | 0.84 |
| ▸ | JAK2 | O60674 | 5/20 | 0.81 |
| ▸ | JAK1 | P23458 | 3/20 | 0.78 |
| ▸ | STAT3 | P40763 | 1/20 | 0.78 |
| ▸ | STAT1 | P42224 | 1/20 | 0.78 |
| ▸ | JAK3 | P52333 | 1/20 | 0.78 |
| ▸ | BMPR2 | Q13873 | 1/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22647268 | 1.00 | TYK2 (0.84) | TYK2JAK2JAK1STAT3STAT1 | |
| SCHEMBL22288321 | 0.94 | TYK2 (0.82) | TYK2JAK2JAK1STAT3STAT1 | |
| SCHEMBL31369050 | 0.92 | TYK2 (0.71) | TYK2JAK2JAK1STAT3STAT1 | |
| SCHEMBL31369053 | 0.92 | TYK2 (0.71) | TYK2JAK2JAK1STAT3STAT1 | |
| SCHEMBL28648935 | 0.92 | TYK2 (0.71) | TYK2JAK2JAK1STAT3STAT1 | |
| SCHEMBL23096153 | 0.91 | TYK2 (0.87) | TYK2JAK2JAK1STAT3STAT1 | |
| SCHEMBL22647341 | 0.91 | TYK2 (1.00) | TYK2JAK2JAK1STAT3STAT1 | |
| SCHEMBL22647338 | 0.91 | TYK2 (0.87) | TYK2JAK2JAK1STAT3STAT1 | |
| SCHEMBL22263494 | 0.91 | TYK2 (0.87) | TYK2JAK2JAK1STAT3STAT1 | |
| SCHEMBL32691810 | 0.91 | TYK2 (0.87) | TYK2JAK2JAK1STAT3STAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113563309-B | Pyridine derivative and preparation method and application thereof | 浙江海正药业股份有限公司 | 2024-12-13 | — | — | CN | disclosed |