Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 9/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 9/20 | 0.34 |
| ▸ | RAF1 | P04049 | 1/20 | 0.32 |
| ▸ | BRAF | P15056 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | GCGR | P47871 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3770812 | 0.99 | SYK (0.35) | SYKPDE3BPDE3ARAF1BRAF | |
| SCHEMBL3142559 | 0.86 | PIK3CD (0.34) | SYKNPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL3147359 | 0.86 | SYK (0.40) | SYKNPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL3151010 | 0.78 | PDE3B (0.34) | PDE3BPDE3A | |
| Hydrochloric Acid SCHEMBL3779595 | 0.77 | PDE3B (0.33) | PDE3BPDE3A | |
| SCHEMBL3151064 | 0.76 | RAF1 (0.38) | PDE3BPDE3ARAF1BRAF | |
| SCHEMBL3151394 | 0.76 | NTRK1 (0.33) | PDE3BPDE3A | |
| SCHEMBL3151084 | 0.75 | CHRNB4 (0.40) | SYKNPC1MAPTRAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL3784272 | 0.75 | NTRK1 (0.33) | PDE3BPDE3A | |
| Hydrochloric Acid SCHEMBL3779005 | 0.74 | CHRNB4 (0.39) | SYKNPC1MAPTRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1979321-B9 | NOVEL PYRIDINYLAMINOALKYLENE- AND PYRIDINYLOXYALKYLENE-CYCLOPROPANAMINES, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SERVIER LAB (FR) | 2010-02-17 | — | — | EP | disclosed |
| EP-1979321-B1 | NOVEL PYRIDINYLAMINOALKYLENE- AND PYRIDINYLOXYALKYLENE-CYCLOPROPANAMINES, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SERVIER LAB (FR) | 2009-07-29 | — | — | EP | disclosed |