SCHEMBL31371607

SCHEMBL31371607

COC(=O)c1ccc(OC)c(S(=O)(=O)Nc2noc3cc(Cn4cccn4)cc(OC)c23)c1

nearest known ligand 0.82

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ KAT7 O95251 20/20 0.82
▸ KAT6A Q92794 20/20 0.82
▸ KAT6B Q8WYB5 15/20 0.82
▸ KAT5 Q92993 15/20 0.82
▸ KAT8 Q9H7Z6 15/20 0.82

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22802424 0.90 KAT6A (1.00) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL22817446 0.88 KAT7 (1.00) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL22817329 0.88 KAT7 (1.00) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL30680835 0.88 KAT7 (0.83) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL22802508 0.88 KAT7 (0.83) KAT7KAT6AKAT6BKAT5KAT8
Prifetrastat SCHEMBL29490368 0.87 KAT7 (0.90) KAT7KAT6AKAT6BKAT5KAT8
Prifetrastat SCHEMBL22802427 0.87 KAT7 (0.90) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL31371929 0.87 KAT7 (0.79) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL22817322 0.87 KAT6A (1.00) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL22829283 0.86 KAT7 (1.00) KAT7KAT6AKAT6BKAT5KAT8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025036382-A1 SULFONAMIDE COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF 上海复宏汉霖生物医药有限公司 2025-02-20 — — WO disclosed
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