SCHEMBL3137307

SCHEMBL3137307

COC(=O)c1cc(C(=O)OC)cc(S(=O)(=O)O)c1.C[PH](c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.46
LCK P06239 1/20 0.45
FYN P06241 1/20 0.45
ALDH1A1 P00352 5/20 0.43
KDM4E B2RXH2 4/20 0.43
HPGD P15428 3/20 0.43
GAA P10253 3/20 0.43
PKM P14618 1/20 0.43
HIF1A Q16665 1/20 0.41
PTGS2 P35354 1/20 0.41
POLB P06746 3/20 0.40
NPSR1 Q6W5P4 1/20 0.40
KMT2A Q03164 1/20 0.40
LMNA P02545 1/20 0.40
MAPT P10636 3/20 0.39
HTT P42858 1/20 0.39
ACLY P53396 2/20 0.39
CASP3 P42574 1/20 0.39
RAB9A P51151 1/20 0.39
SENP8 Q96LD8 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3915612 0.90 TSHR (0.47) TSHRLCKFYNALDH1A1KDM4E
SCHEMBL28676642 0.85 KDM4E (0.47) TSHRALDH1A1KDM4EHPGDGAA
SCHEMBL3910145 0.85 TSHR (0.42) TSHRLCKFYNALDH1A1KDM4E
SCHEMBL6555898 0.83 HPGD (0.44) TSHRLCKFYNALDH1A1KDM4E
SCHEMBL124987 0.83 LCK (0.57) TSHRLCKFYNALDH1A1KDM4E
SCHEMBL29620305 0.83 LCK (0.57) TSHRLCKFYNALDH1A1KDM4E
SCHEMBL10434882 0.82 TSHR (0.49) TSHRLCKFYNALDH1A1KDM4E
SCHEMBL9440606 0.81 TSHR (0.47) TSHRLCKFYNALDH1A1KDM4E
SCHEMBL1818497 0.81 LCK (0.55) TSHRLCKFYNALDH1A1KDM4E
SCHEMBL472701 0.81 LCK (0.55) TSHRLCKFYNALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7641819-B2 Biasable transfer composition and member EASTMAN KODAK COMPANY (US) 2010-01-05 US disclosed
US-20070075295-A1 Biasable transfer composition and member EASTMAN KODAK COMPANY 2007-04-05 US disclosed