Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 7/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 3/20 | 0.40 |
| ▸ | DRD4 | P21917 | 2/20 | 0.40 |
| ▸ | WDR5 | P61964 | 2/20 | 0.40 |
| ▸ | DRD3 | P35462 | 2/20 | 0.39 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.39 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31373268 | 0.95 | BCHE (0.42) | BCHETP53THRB | |
| SCHEMBL31373242 | 0.94 | BCHE (0.44) | BCHETP53THRBWDR5PABPC1 | |
| SCHEMBL31373254 | 0.93 | BCHE (0.43) | BCHETP53THRBWDR5PABPC1 | |
| SCHEMBL31373285 | 0.91 | BCHE (0.42) | BCHETP53THRBCNR2KDM4E | |
| SCHEMBL31373286 | 0.91 | KDM4E (0.45) | BCHETP53THRBKDM4ELMNA | |
| SCHEMBL31373303 | 0.90 | BCHE (0.41) | BCHETP53THRBWDR5CNR2 | |
| SCHEMBL31373297 | 0.90 | BCHE (0.47) | BCHETP53THRBKDM4ELMNA | |
| SCHEMBL31373262 | 0.89 | BCHE (0.48) | BCHETP53THRBLMNA | |
| SCHEMBL31373276 | 0.89 | TP53 (0.49) | BCHETP53THRBWDR5LMNA | |
| SCHEMBL31373267 | 0.88 | BCHE (0.42) | BCHETP53THRBWDR5KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025027117-A1 | CARBOXAMIDE-4-QUINOLINE COMPOUNDS WITH ANTHELMINTIC ACTIVITY | INTERVET INTERNATIONAL B.V. (NL) | 2025-02-06 | — | — | WO | claimed |
| WO-2025027117-A1 | CARBOXAMIDE-4-QUINOLINE COMPOUNDS WITH ANTHELMINTIC ACTIVITY | INTERVET INTERNATIONAL B.V. (NL) | 2025-02-06 | — | — | WO | disclosed |