Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | USP8 | P40818 | 3/20 | 0.31 |
| ▸ | USP7 | Q93009 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | USP47 | Q96K76 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24108192 | 1.00 | CYP2A6 (0.34) | CYP2A6ALDH1A1KDM4EPOLBUSP8 | |
| SCHEMBL2215194 | 0.84 | KMT2A (0.32) | ALDH1A1KDM4EPOLBUSP8USP7 | |
| SCHEMBL26618447 | 0.82 | KDM4E (0.31) | ALDH1A1KDM4EPOLB | |
| SCHEMBL29549624 | 0.82 | CYP2A6 (0.35) | CYP2A6ALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL837132 | 0.82 | CYP2A6 (0.35) | CYP2A6ALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL25990988 | 0.80 | SOS2 (0.34) | ALDH1A1USP8USP7MEN1MAPT | |
| SCHEMBL9900615 | 0.78 | CYP2A6 (0.33) | CYP2A6ALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL31361151 | 0.78 | CYP2A6 (0.33) | CYP2A6ALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL29599530 | 0.74 | PDCD1LG2 (0.43) | — | |
| SCHEMBL20719692 | 0.74 | PDCD1LG2 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119212988-A | Kinesin KIF18A inhibitor and application thereof | 上海湃隆生物科技有限公司 | 2024-12-27 | — | — | CN | disclosed |