Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LATS1 | O95835 | 20/20 | 0.76 |
| ▸ | LATS2 | Q9NRM7 | 16/20 | 0.76 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.63 |
| ▸ | PRKCH | P24723 | 1/20 | 0.63 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.63 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.63 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.63 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20547759 | 0.86 | LATS1 (1.00) | LATS1LATS2 | |
| SCHEMBL25269947 | 0.85 | LATS1 (0.78) | LATS1LATS2 | |
| SCHEMBL20548041 | 0.83 | LATS1 (1.00) | LATS1LATS2 | |
| SCHEMBL20547737 | 0.82 | LATS1 (1.00) | LATS1LATS2 | |
| SCHEMBL20547818 | 0.82 | LATS1 (1.00) | LATS1LATS2 | |
| SCHEMBL31375146 | 0.82 | LATS1 (0.88) | LATS1LATS2 | |
| SCHEMBL20574404 | 0.81 | LATS1 (0.84) | LATS1LATS2 | |
| SCHEMBL26177107 | 0.81 | LATS1 (1.00) | LATS1LATS2 | |
| SCHEMBL20574246 | 0.81 | LATS1 (1.00) | LATS1LATS2ROCK2PRKCHPRKCQ | |
| SCHEMBL20547801 | 0.81 | LATS1 (1.00) | LATS1LATS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114621222-B | 6-6 Fused bicyclic heteroaryl compounds and their use as LATS inhibitors | 诺华股份有限公司 | 2024-12-17 | — | — | CN | claimed |