Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 3/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.31 |
| ▸ | AURKA | O14965 | 6/20 | 0.30 |
| ▸ | PDPK1 | O15530 | 6/20 | 0.30 |
| ▸ | AURKB | Q96GD4 | 6/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31628209 | 1.00 | GAA (0.37) | GAAKDM4EPSMB8NPC1RAB9A | |
| SCHEMBL29797169 | 0.90 | GAA (0.37) | GAAPSMB8EPHX2LIPGBRD4 | |
| SCHEMBL31375540 | 0.90 | GAA (0.37) | GAAPSMB8EPHX2LIPGBRD4 | |
| SCHEMBL31628170 | 0.90 | GAA (0.37) | GAAPSMB8EPHX2LIPGBRD4 | |
| SCHEMBL26962347 | 0.90 | GAA (0.37) | GAAPSMB8EPHX2LIPGBRD4 | |
| SCHEMBL31628179 | 0.86 | HDAC6 (0.37) | GAAPSMB8EPHX2LIPGBRD4 | |
| SCHEMBL31375586 | 0.86 | GAA (0.35) | GAAPSMB8EPHX2LIPGBRD4 | |
| SCHEMBL30830302 | 0.86 | GAA (0.34) | GAAPSMB8EPHX2LIPG | |
| SCHEMBL31375572 | 0.85 | GAA (0.34) | GAAPSMB8LIPGBRD4 | |
| SCHEMBL31628193 | 0.85 | GAA (0.34) | GAAPSMB8LIPGBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119677733-A | Bicyclic tetrahydrothiazepine derivatives | 豪夫迈·罗氏有限公司 | 2025-03-21 | — | — | CN | disclosed |