Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | CTSD | P07339 | 4/20 | 0.31 |
| ▸ | BACE1 | P56817 | 3/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.30 |
| ▸ | RELA | Q04206 | 1/20 | 0.30 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26962790 | 0.91 | GAA (0.33) | GAA | |
| SCHEMBL30830298 | 0.91 | GAA (0.33) | GAAEPHX2 | |
| SCHEMBL29796806 | 0.91 | GAA (0.33) | GAA | |
| SCHEMBL26962176 | 0.89 | GAA (0.38) | GAAEPHX2NFKB1NFKB2RELA | |
| SCHEMBL31375609 | 0.87 | GAA (0.32) | GAA | |
| SCHEMBL32670510 | 0.86 | GAA (0.33) | GAA | |
| SCHEMBL20263999 | 0.85 | GAA (0.40) | GAAEPHX2CTSDBACE1NFKB1 | |
| SCHEMBL27121024 | 0.85 | GAA (0.40) | GAAEPHX2CTSDBACE1NFKB1 | |
| SCHEMBL29797018 | 0.84 | GAA (0.38) | GAAEPHX2CTSDBACE1NFKB1 | |
| SCHEMBL31374892 | 0.84 | GAA (0.38) | GAAEPHX2CTSDBACE1NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568959-A1 | BICYCLIC TETRAHYDROTHIAZEPINE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2025-06-18 | — | — | EP | disclosed |
| CN-119677733-A | Bicyclic tetrahydrothiazepine derivatives | 豪夫迈·罗氏有限公司 | 2025-03-21 | — | — | CN | disclosed |