Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LATS1 | O95835 | 19/20 | 0.40 |
| ▸ | LATS2 | Q9NRM7 | 16/20 | 0.40 |
| ▸ | KDM5A | P29375 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20547814 | 0.80 | LATS1 (0.67) | LATS1LATS2 | |
| SCHEMBL20547472 | 0.78 | LATS1 (0.66) | LATS1LATS2 | |
| SCHEMBL20547863 | 0.78 | LATS1 (0.67) | LATS1LATS2 | |
| SCHEMBL20574533 | 0.77 | LATS1 (0.67) | LATS1LATS2 | |
| SCHEMBL14529396 | 0.75 | CYP1A2 (0.51) | LATS1 | |
| SCHEMBL31375771 | 0.75 | LATS1 (0.32) | LATS1 | |
| SCHEMBL20573782 | 0.74 | LATS1 (0.69) | LATS1LATS2 | |
| SCHEMBL26177196 | 0.73 | LATS1 (0.70) | LATS1LATS2 | |
| SCHEMBL30112218 | 0.73 | LATS1 (0.70) | LATS1LATS2 | |
| SCHEMBL31375757 | 0.72 | LATS1 (0.49) | LATS1LATS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114621222-B | 6-6 Fused bicyclic heteroaryl compounds and their use as LATS inhibitors | 诺华股份有限公司 | 2024-12-17 | — | — | CN | disclosed |