Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LATS1 | O95835 | 17/20 | 1.00 |
| ▸ | LATS2 | Q9NRM7 | 13/20 | 1.00 |
| ▸ | PRKCI | P41743 | 1/20 | 0.46 |
| ▸ | IGF1R | P08069 | 1/20 | 0.45 |
| ▸ | CDK2 | P24941 | 1/20 | 0.45 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.45 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20547424 | 1.00 | LATS1 (1.00) | LATS1LATS2PRKCIIGF1RCDK2 | |
| SCHEMBL20573806 | 0.80 | LATS1 (1.00) | LATS1LATS2 | |
| SCHEMBL31375902 | 0.80 | LATS1 (1.00) | LATS1LATS2 | |
| SCHEMBL31375140 | 0.80 | LATS1 (1.00) | LATS1LATS2 | |
| SCHEMBL20574378 | 0.80 | LATS1 (1.00) | LATS1LATS2 | |
| SCHEMBL29650605 | 0.77 | LATS1 (1.00) | LATS1LATS2 | |
| SCHEMBL20548228 | 0.77 | LATS1 (1.00) | LATS1LATS2 | |
| SCHEMBL20573775 | 0.76 | LATS1 (1.00) | LATS1LATS2 | |
| SCHEMBL20574248 | 0.76 | LATS1 (0.67) | LATS1LATS2 | |
| SCHEMBL30309302 | 0.76 | LATS1 (1.00) | LATS1LATS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114621222-B | 6-6 Fused bicyclic heteroaryl compounds and their use as LATS inhibitors | 诺华股份有限公司 | 2024-12-17 | — | — | CN | disclosed |