Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.34 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.34 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | APLNR | P35414 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19373473 | 0.90 | FOLH1 (0.43) | TDP1FOLH1MEN1KMT2AMAPK1 | |
| SCHEMBL18697068 | 0.85 | MEN1 (0.42) | TDP1FOLH1MEN1KMT2AMAPK1 | |
| SCHEMBL19373169 | 0.83 | MEN1 (0.40) | TDP1FOLH1MEN1KMT2AMAPK1 | |
| SCHEMBL24940537 | 0.83 | FOLH1 (0.42) | TDP1FOLH1MEN1KMT2AMAPK1 | |
| SCHEMBL23270089 | 0.82 | FOLH1 (0.39) | TDP1FOLH1MEN1KMT2AMAPK1 | |
| SCHEMBL23225441 | 0.81 | FOLH1 (0.38) | TDP1FOLH1MEN1KMT2AMAPK1 | |
| SCHEMBL25596897 | 0.80 | KMT2A (0.40) | TDP1FOLH1MEN1KMT2AMAPK1 | |
| SCHEMBL29935596 | 0.80 | TDP1 (0.37) | TDP1FOLH1MEN1KMT2AMAPK1 | |
| SCHEMBL16118673 | 0.79 | MEN1 (0.46) | TDP1FOLH1MEN1KMT2AMAPK1 | |
| SCHEMBL29470587 | 0.79 | FOLH1 (0.40) | TDP1FOLH1MEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119390720-B | Bicyclo [1.1.1] pentane compound for targeting and combining fibroblast activation protein and application thereof | 杭州景嘉航生物医药科技有限公司 | 2025-04-01 | — | — | CN | disclosed |
| CN-119390720-A | Bicyclo [1.1.1] pentane compound for targeting and combining fibroblast activation protein and application thereof | 杭州景嘉航生物医药科技有限公司 | 2025-02-07 | — | — | CN | disclosed |