Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LATS1 | O95835 | 15/20 | 1.00 |
| ▸ | LATS2 | Q9NRM7 | 8/20 | 1.00 |
| ▸ | RPS6KA5 | O75582 | 5/20 | 0.45 |
| ▸ | RPS6KA4 | O75676 | 1/20 | 0.41 |
| ▸ | PRKCH | P24723 | 1/20 | 0.38 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.38 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20574634 | 1.00 | LATS1 (1.00) | LATS1LATS2RPS6KA5RPS6KA4PRKCH | |
| SCHEMBL31375152 | 0.80 | LATS1 (1.00) | LATS1LATS2 | |
| SCHEMBL20574535 | 0.80 | LATS1 (1.00) | LATS1LATS2 | |
| SCHEMBL26157392 | 0.70 | LATS1 (0.67) | LATS1LATS2PRKCHPRKCEPRKCD | |
| SCHEMBL20574445 | 0.69 | LATS1 (0.68) | LATS1LATS2PRKCHPRKCEPRKCD | |
| SCHEMBL20547465 | 0.69 | LATS1 (1.00) | LATS1LATS2PRKCHPRKCEPRKCD | |
| SCHEMBL31375817 | 0.69 | LATS1 (1.00) | LATS1LATS2PRKCHPRKCEPRKCD | |
| SCHEMBL20547846 | 0.69 | LATS1 (1.00) | LATS1LATS2PRKCHPRKCEPRKCD | |
| SCHEMBL30377003 | 0.68 | LATS1 (0.52) | LATS1LATS2RPS6KA5RPS6KA4 | |
| SCHEMBL28331409 | 0.68 | LATS1 (0.52) | LATS1LATS2RPS6KA5RPS6KA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114621222-B | 6-6 Fused bicyclic heteroaryl compounds and their use as LATS inhibitors | 诺华股份有限公司 | 2024-12-17 | — | — | CN | disclosed |