Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 13/20 | 0.57 |
| ▸ | NUAK1 | O60285 | 1/20 | 0.49 |
| ▸ | JAK2 | O60674 | 2/20 | 0.47 |
| ▸ | JAK3 | P52333 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3136376 | 1.00 | NTRK1 (0.57) | NTRK1NUAK1JAK2JAK3 | |
| SCHEMBL3136390 | 1.00 | NTRK1 (0.57) | NTRK1NUAK1JAK2JAK3 | |
| SCHEMBL3019865 | 0.88 | NTRK1 (0.64) | NTRK1NUAK1JAK2JAK3 | |
| SCHEMBL27711294 | 0.87 | NTRK1 (0.56) | NTRK1NUAK1JAK2JAK3 | |
| SCHEMBL3134400 | 0.87 | NTRK1 (0.58) | NTRK1NUAK1JAK2JAK3 | |
| SCHEMBL3134412 | 0.87 | NTRK1 (0.58) | NTRK1NUAK1JAK2JAK3 | |
| SCHEMBL3137395 | 0.87 | NTRK1 (0.56) | NTRK1NUAK1JAK2JAK3 | |
| SCHEMBL3132267 | 0.86 | NTRK1 (0.50) | NTRK1NUAK1 | |
| SCHEMBL3132279 | 0.86 | NTRK1 (0.50) | NTRK1NUAK1 | |
| SCHEMBL3124294 | 0.85 | NUAK1 (0.68) | NTRK1NUAK1JAK2JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1853602-B1 | CHEMICAL COMPOUNDS | ASTRAZENECA AB (SE) | 2010-07-14 | — | — | EP | disclosed |