SCHEMBL3137774

SCHEMBL3137774

c1ccc(-c2c3ccccc3c(-c3ccccc3)c3c(-c4ccccc4)c4ccccc4c(-c4ccccc4)c23)cc1.c1ccc(-c2ccc3cc4ccccc4cc3c2-c2ccccc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 7/20 0.44
ESR2 Q92731 7/20 0.44
MEN1 O00255 4/20 0.42
KMT2A Q03164 4/20 0.42
KDM4E B2RXH2 4/20 0.42
ALDH1A1 P00352 3/20 0.42
MAPT P10636 2/20 0.42
HPGD P15428 2/20 0.42
MPI P34949 1/20 0.42
NQO2 P16083 1/20 0.40
HIF1A Q16665 1/20 0.39
CYP1B1 Q16678 1/20 0.39
HSD17B10 Q99714 1/20 0.39
GPR84 Q9NQS5 3/20 0.39
ALOX5 P09917 1/20 0.38
SOS1 Q07889 1/20 0.37
RECQL P46063 1/20 0.37
ERBB2 P04626 1/20 0.37
CYP1A2 P05177 1/20 0.37
FYN P06241 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31254074 0.91 ESR1 (0.46) ESR1ESR2MEN1KMT2AKDM4E
Benzene SCHEMBL27418790 0.91 ESR1 (0.46) ESR1ESR2MEN1KMT2AKDM4E
SCHEMBL30661015 0.91 ESR1 (0.46) ESR1ESR2MEN1KMT2AKDM4E
SCHEMBL32080 0.91 ESR1 (0.46) ESR1ESR2MEN1KMT2AKDM4E
SCHEMBL28463046 0.90 ESR1 (0.44) ESR1ESR2MEN1KMT2AKDM4E
Methane SCHEMBL27643843 0.90 ESR1 (0.44) ESR1ESR2MEN1KMT2AKDM4E
SCHEMBL3202035 0.90 ESR1 (0.44) ESR1ESR2MEN1KMT2AKDM4E
SCHEMBL49889 0.90 ESR1 (0.44) ESR1ESR2MEN1KMT2AKDM4E
SCHEMBL30484243 0.90 ESR1 (0.44) ESR1ESR2MEN1KMT2AKDM4E
Ammonia Solution, Strong SCHEMBL28014470 0.90 ESR1 (0.44) ESR1ESR2MEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100003679-A1 ASSESSMENT OF CELLULAR COMPOSITION AND FRACTIONAL VIABILITY AND USES THEREOF UNIVERSITY OF MIAMI (US) 2010-01-07 US disclosed
EP-2029726-A2 ASSESSMENT OF CELLULAR COMPOSITION AND FRACTIONAL VIABILITY AND USES THEREOF University of Miami (US) 2009-03-04 EP disclosed
WO-2007146811-A2 ASSESSMENT OF CELLULAR COMPOSITION AND FRACTIONAL VIABILITY AND USES THEREOF UNIVERSITY OF MIAMI (US) 2007-12-21 WO disclosed
US-7223851-B2 Nucleic acid-binding polymers GENERAL DYNAMICS ADVANCED INFORMATION SYSTEMS, INC. (US) 2007-05-29 US disclosed
US-20040157217-A1 Nucleic acid-binding polymers VERIDIAN SYSTEMS DIVISION 2004-08-12 US disclosed
US-20040152085-A1 Surface for collection and/or purification of nucleic acids VERIDIAN SYSTEMS DIVISION 2004-08-05 US disclosed
US-5972692-A Gene detection method KABUSHIKI KAISHA TOSHIBA (JP) 1999-10-26 US disclosed
US-5776672-A Gene detection method KABUSHIKI KAISHA TOSHIBA (JP) 1998-07-07 US disclosed