SCHEMBL31379527

SCHEMBL31379527

O=C(OCc1ccccc1)N1CCC(NC2CC2)C1

nearest known ligand 0.61

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.61
NPC1 O15118 2/20 0.61
RAB9A P51151 2/20 0.61
CYP2C19 P33261 1/20 0.59
HSD11B1 P28845 1/20 0.55
F13A1 P00488 3/20 0.55
TGM2 P21980 3/20 0.55
TGM1 P22735 3/20 0.55
GRIN2B Q13224 3/20 0.53
HTT P42858 1/20 0.53
ENPP2 Q13822 3/20 0.52
MEN1 O00255 2/20 0.52
KMT2A Q03164 2/20 0.52
NPSR1 Q6W5P4 1/20 0.52
CYP2D6 P10635 1/20 0.52
CYP2C9 P11712 1/20 0.52
USP30 Q70CQ3 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30229262 1.00 SMN1; SMN2 (0.61) SMN1; SMN2NPC1RAB9ACYP2C19HSD11B1
SCHEMBL30229265 1.00 SMN1; SMN2 (0.61) SMN1; SMN2NPC1RAB9ACYP2C19HSD11B1
SCHEMBL30229159 0.95 SMN1; SMN2 (0.59) SMN1; SMN2NPC1RAB9ACYP2C19HSD11B1
SCHEMBL30229034 0.95 SMN1; SMN2 (0.59) SMN1; SMN2NPC1RAB9ACYP2C19HSD11B1
SCHEMBL2273359 0.94 SMN1; SMN2 (0.57) SMN1; SMN2NPC1RAB9ACYP2C19HSD11B1
SCHEMBL3086491 0.93 SMN1; SMN2 (0.70) SMN1; SMN2NPC1RAB9ACYP2C19F13A1
SCHEMBL30229230 0.92 MEN1 (0.60) SMN1; SMN2NPC1RAB9ACYP2C19HSD11B1
SCHEMBL31714068 0.89 SMN1; SMN2 (0.55) SMN1; SMN2NPC1RAB9ACYP2C19HSD11B1
SCHEMBL30228915 0.89 SMN1; SMN2 (0.55) SMN1; SMN2NPC1RAB9ACYP2C19HSD11B1
SCHEMBL13434275 0.89 SMN1; SMN2 (0.54) SMN1; SMN2NPC1RAB9ACYP2C19HSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025036241-A1 COMPOUNDS AND METHODS FOR MODULATING RNA SPLICING RIBOPEUTIC INC. (CN) 2025-02-20 WO disclosed