Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 19/20 | 0.61 |
| ▸ | S1PR5 | Q9H228 | 16/20 | 0.61 |
| ▸ | S1PR4 | O95977 | 14/20 | 0.61 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.61 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.46 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3127782 | 0.88 | S1PR1 (0.79) | S1PR1S1PR5S1PR4S1PR3MAP4K4 | |
| SCHEMBL3135332 | 0.86 | S1PR1 (0.61) | S1PR1S1PR5S1PR4S1PR3MAP4K4 | |
| SCHEMBL3136507 | 0.83 | S1PR1 (0.59) | S1PR1S1PR5S1PR4S1PR3MAP4K4 | |
| SCHEMBL3134976 | 0.81 | S1PR1 (0.79) | S1PR1S1PR5S1PR4S1PR3 | |
| SCHEMBL29151625 | 0.76 | S1PR1 (1.00) | S1PR1S1PR5S1PR4S1PR3 | |
| SCHEMBL5383882 | 0.76 | S1PR1 (1.00) | S1PR1S1PR5S1PR4S1PR3 | |
| SCHEMBL20975841 | 0.74 | S1PR1 (0.74) | S1PR1S1PR5S1PR4S1PR3 | |
| SCHEMBL3137733 | 0.74 | S1PR1 (0.47) | S1PR1S1PR5S1PR4S1PR3MAP4K4 | |
| SCHEMBL3135322 | 0.73 | S1PR1 (0.79) | S1PR1S1PR5S1PR4S1PR3MAP4K4 | |
| SCHEMBL3137868 | 0.73 | S1PR1 (0.56) | S1PR1S1PR5S1PR4S1PR3MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1873153-B1 | 3-AZETIDINECARBOXYLIC ACID DERIVATIVES FOR USE AS IMMUNOSUPPRESSANTS | DAIICHI SANKYO CO LTD (JP) | 2010-07-07 | — | — | EP | claimed |