SCHEMBL3138002

SCHEMBL3138002

Brc1ccc(Br)cc1.[MgH2]

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9496102 1.00 CYP2A6 (0.89)
SCHEMBL18508 0.94
Hydrogen Sulfide SCHEMBL27842395 0.89 CYP2A6 (0.89)
Methane SCHEMBL21489530 0.89 CYP2A6 (0.89)
Water SCHEMBL28199836 0.89
Iodide SCHEMBL28192032 0.89
Iodide SCHEMBL28126419 0.89 CYP2A6 (0.89)
SCHEMBL21518322 0.89
Fluoride SCHEMBL27921066 0.89 CYP2A6 (0.89)
Water SCHEMBL27566591 0.89 CYP2A6 (0.89)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118619890-B Method for synthesizing UV-627 key intermediate based on photocatalysis strategy 武汉纺织大学 2025-02-14 CN disclosed
CN-118619890-A Method for synthesizing UV-627 key intermediate based on photocatalysis strategy 武汉纺织大学 2024-09-10 CN disclosed
CN-114874080-B Preparation method of 4,4' -difluorobenzophenone 绍兴久孚新材料科技有限公司 2024-08-02 CN disclosed
CN-116964034-A Heterocyclic ring P2Y 14 Receptor antagonists 美国卫生和人力服务部 2023-10-27 CN disclosed
CN-111647011-B Preparation method of monohalogenated phenylboronic acid 宁夏中星显示材料有限公司 2023-04-07 CN disclosed
EP-3638643-B1 PROCESS FOR THE PREPARATION OF SEMIFLUORINATED ALKANES USING GRIGNARD REAGENTS NOVALIQ GMBH (DE) 2023-01-18 EP disclosed
CN-112110789-B Synthetic method of 2,2',3,3',5,5',6,6' -octafluoro-4-halobiphenyl 浙江中欣氟材股份有限公司 2022-05-03 CN disclosed
CN-108368094-B Non-steroidal glucocorticoid receptor modulators for topical drug delivery 利奥制药有限公司 2021-07-02 CN disclosed
EP-3293184-B1 PYRIMIDINE CARBOXAMIDES AS SODIUM CHANNEL BLOCKERS PURDUE PHARMA LP (US) 2020-12-16 EP disclosed
US-20200339492-A1 PROCESS FOR THE PREPARATION OF SEMIFLUORINATED ALKANES USING GRIGNARD REAGENTS NOVALIQ GMBH (DE) 2020-10-29 US disclosed
EP-0850221-A1 META-GUANIDINE, UREA, THIOUREA OR AZACYCLIC AMINO BENZOIC ACID DERIVATIVES AS INTEGRIN ANTAGONISTS G.D. SEARLE & CO. (US) 1998-07-01 EP disclosed
WO-1997008145-A1 META-GUANIDINE, UREA, THIOUREA OR AZACYCLIC AMINO BENZOIC ACID DERIVATIVES AS INTEGRIN ANTAGONISTS G.D. SEARLE & CO. (US) 1997-03-06 WO disclosed
US-5446162-A Process for the production of 7-acylindoles LONAZ LTD. (CH) 1995-08-29 US disclosed
US-5380857-A Process for the production of 7-acylindoles LONZA LTD. (CH) 1995-01-10 US disclosed
US-4442225-A Catalytic component for polymerization of α-olefin and method for homo- or co-polymerization of α-olefin TOYO STAUFFER CHEMICAL CO., LTD. (JP) 1984-04-10 US disclosed
EP-0103120-A2 Process for producing a catalyst component used for the polymerization of alpha-olefins TOYO STAUFFER CHEMICAL CO. LTD. (JP) 1984-03-21 EP disclosed
EP-0102503-A2 Process for producing a catalyst component used for the polymerization of alpha-olefins TOYO STAUFFER CHEMICAL CO. LTD. (JP) 1984-03-14 EP disclosed
EP-0024943-B1 5,6,7-TRINOR-4,8-INTER-M-PHENYLENE PGI2 DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM TORAY INDUSTRIES, INC. (JP) 1983-08-17 EP disclosed
US-4301164-A FOR USE AS ANTIULCER AGENTS, HYPOTENSIVE AGENTS, ANTITHROMBOSIC AGENTS TORAY INDUSTRIES, INC. (JP) 1981-11-17 US disclosed
EP-0024943-A1 5,6,7-Trinor-4,8-inter-m-phenylene PGI2 derivatives and pharmaceutical compositions containing them TORAY INDUSTRIES, INC. (JP) 1981-03-11 EP disclosed