Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.46 |
| ▸ | RORC | P51449 | 3/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PREP | P48147 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31187595 | 0.90 | NR1H2 (0.49) | NR1H2RORCUSP2SMN1; SMN2GPR119 | |
| SCHEMBL6112357 | 0.84 | NR1H2 (0.40) | NR1H2RORCUSP2SMN1; SMN2GPR119 | |
| SCHEMBL31049143 | 0.83 | NR1H2 (0.43) | NR1H2RORCUSP2SMN1; SMN2NAMPT | |
| SCHEMBL459742 | 0.81 | NR1H2 (0.50) | NR1H2RORCUSP2SMN1; SMN2GPR119 | |
| SCHEMBL4684359 | 0.79 | NR1H2 (0.49) | NR1H2RORCUSP2SMN1; SMN2GPR119 | |
| SCHEMBL29655394 | 0.79 | NR1H2 (0.49) | NR1H2RORCUSP2SMN1; SMN2GPR119 | |
| SCHEMBL16903485 | 0.79 | NR1H2 (0.51) | NR1H2RORCUSP2SMN1; SMN2GPR119 | |
| SCHEMBL20647830 | 0.79 | NR1H2 (0.51) | NR1H2RORCUSP2SMN1; SMN2GPR119 | |
| SCHEMBL20647832 | 0.79 | NR1H2 (0.51) | NR1H2RORCUSP2SMN1; SMN2GPR119 | |
| SCHEMBL16903487 | 0.79 | NR1H2 (0.51) | NR1H2RORCUSP2SMN1; SMN2GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025026903-A1 | IMIDAZO PYRIMIDINE COMPOUNDS FOR THE TREATMENT OF CANCER | BAYER AKTIENGESELLSCHAFT (DE) | 2025-02-06 | — | — | WO | disclosed |