Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23203394 | 0.78 | TP53 (0.35) | TP53 | |
| SCHEMBL104478 | 0.77 | TSHR (0.45) | ALDH1A1TP53TSHRMAPTPTGS1 | |
| SCHEMBL15908131 | 0.77 | TSHR (0.45) | ALDH1A1TP53TSHRMAPTPTGS1 | |
| SCHEMBL285426 | 0.77 | TSHR (0.45) | ALDH1A1TP53TSHRMAPTPTGS1 | |
| SCHEMBL1924478 | 0.77 | TSHR (0.45) | ALDH1A1TP53TSHRMAPTPTGS1 | |
| SCHEMBL18832123 | 0.77 | TSHR (0.45) | ALDH1A1TP53TSHRMAPTPTGS1 | |
| SCHEMBL12033977 | 0.71 | — | — | |
| SCHEMBL27886273 | 0.71 | — | — | |
| SCHEMBL2954030 | 0.71 | — | — | |
| SCHEMBL13176928 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100003701-A1 | COVALENT MODIFICATION AND CONJUGATION OF LUCIFERASE | CARDIOGENICS INC. (CA) | 2010-01-07 | — | — | US | disclosed |
| US-20070254311-A1 | Covalent modification and conjugation of luciferase | CARDIOGENICS INC. (CA) | 2007-11-01 | — | — | US | disclosed |
| US-4082768-A | NEW IMIDES OF UNSATURATED DICARBOXYLIC ACIDS, PROCESSES FOR THEIR MANUFACTURE, AND THEIR USE | CIBA-GEIGY CORPORATION (US) | 1978-04-04 | — | — | US | disclosed |