Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 5/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3767949 | 0.99 | CHRNB4 (0.39) | CHRNB4CHRNA3CHRNA7FFAR4 | |
| SCHEMBL3147232 | 0.89 | CHRNB4 (0.39) | CHRNB4CHRNA3CHRNA7FFAR4 | |
| SCHEMBL3147247 | 0.89 | CHRNB4 (0.42) | CHRNB4CHRNA3CHRNA7FFAR4 | |
| SCHEMBL3155946 | 0.89 | FFAR4 (0.41) | CHRNB4CHRNA3CHRNA7FFAR4 | |
| Hydrochloric Acid SCHEMBL3147383 | 0.88 | CHRNB4 (0.39) | CHRNB4CHRNA3CHRNA7FFAR4 | |
| Hydrochloric Acid SCHEMBL3776694 | 0.88 | CHRNB4 (0.41) | CHRNB4CHRNA3CHRNA7FFAR4 | |
| SCHEMBL3145927 | 0.88 | CHRNB4 (0.38) | CHRNB4CHRNA3CHRNA7FFAR4 | |
| Hydrochloric Acid SCHEMBL3774060 | 0.88 | FFAR4 (0.40) | CHRNB4CHRNA3CHRNA7FFAR4 | |
| SCHEMBL3154920 | 0.87 | MAP4K4 (0.35) | CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL3151864 | 0.87 | CHRNB4 (0.40) | CHRNB4CHRNA3CHRNA7FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1979321-B9 | NOVEL PYRIDINYLAMINOALKYLENE- AND PYRIDINYLOXYALKYLENE-CYCLOPROPANAMINES, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SERVIER LAB (FR) | 2010-02-17 | — | — | EP | disclosed |
| EP-1979321-B1 | NOVEL PYRIDINYLAMINOALKYLENE- AND PYRIDINYLOXYALKYLENE-CYCLOPROPANAMINES, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SERVIER LAB (FR) | 2009-07-29 | — | — | EP | disclosed |