Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10788280 | 1.00 | ACE (0.36) | ACEALDH1A1POLBKDM4EGMNN | |
| SCHEMBL31384130 | 1.00 | ACE (0.36) | ACEALDH1A1POLBKDM4EGMNN | |
| SCHEMBL14615080 | 0.81 | — | — | |
| SCHEMBL14943439 | 0.81 | — | — | |
| SCHEMBL31289148 | 0.81 | KDM4E (0.41) | ALDH1A1POLBKDM4EGMNNUSP2 | |
| SCHEMBL16579832 | 0.76 | — | — | |
| SCHEMBL14638429 | 0.76 | — | — | |
| SCHEMBL31557729 | 0.74 | KMT2A (0.60) | ALDH1A1ALOX15HSD17B10TDP1MAPT | |
| SCHEMBL6629553 | 0.70 | — | — | |
| SCHEMBL15291832 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024250985-A1 | TOLL-LIKE RECEPTOR AGONIST HETEROCYCLIC DERIVATIVE, PREPARATION THEREOF, AND USE THEREOF | 上海维申医药有限公司 | 2024-12-12 | — | — | WO | disclosed |