Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM4 | O15151 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | CASP3 | P42574 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31385405 | 0.88 | MDM4 (0.47) | MDM4TP53CASP3KMT2AEPHX2 | |
| SCHEMBL3309050 | 0.87 | MDM4 (0.52) | MDM4TP53CASP3KMT2AEPHX2 | |
| SCHEMBL29423449 | 0.87 | MDM4 (0.52) | MDM4TP53CASP3KMT2AEPHX2 | |
| SCHEMBL31370735 | 0.87 | MDM4 (0.52) | MDM4TP53CASP3KMT2AEPHX2 | |
| SCHEMBL2367138 | 0.87 | MDM4 (0.52) | MDM4TP53CASP3KMT2AEPHX2 | |
| SCHEMBL29793991 | 0.87 | MDM4 (0.52) | MDM4TP53CASP3KMT2AEPHX2 | |
| SCHEMBL29738269 | 0.87 | MDM4 (0.50) | MDM4TP53CASP3KMT2AEPHX2 | |
| SCHEMBL5839367 | 0.87 | KMT2A (0.52) | MDM4TP53CASP3KMT2AEPHX2 | |
| SCHEMBL7391110 | 0.87 | KMT2A (0.52) | MDM4TP53CASP3KMT2AEPHX2 | |
| SCHEMBL1486273 | 0.87 | KMT2A (0.52) | MDM4TP53CASP3KMT2AEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025038747-A1 | MODIFIED THIOSTREPTON-INSPIRED COMPOUNDS FOR TREATMENT OF CANCER AND PREPARATION THEREOF | RS ONCOLOGY, LLC (US) | 2025-02-20 | — | — | WO | disclosed |