Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 6/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HTR1E | P28566 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL380893 | 0.84 | PREP (0.57) | PREPLMNAALDH1A1HSD17B10MEN1 | |
| SCHEMBL31385580 | 0.80 | MEN1 (0.49) | PREPLMNAALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL25288720 | 0.80 | PREP (0.57) | PREPALDH1A1CYP1A2CYP3A4TSHR | |
| SCHEMBL25288719 | 0.80 | PREP (0.57) | PREPALDH1A1CYP1A2CYP3A4TSHR | |
| SCHEMBL25288721 | 0.80 | PREP (0.57) | PREPALDH1A1CYP1A2CYP3A4TSHR | |
| SCHEMBL31385578 | 0.79 | PREP (0.53) | PREPLMNAALDH1A1HSD17B10TSHR | |
| SCHEMBL31385603 | 0.78 | PREP (0.52) | PREPLMNAALDH1A1MAPTHTT | |
| SCHEMBL31385600 | 0.78 | CYP1A2 (0.59) | PREPALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL31385651 | 0.78 | PREP (0.54) | PREPLMNAALDH1A1CYP3A4SMN1; SMN2 | |
| SCHEMBL31385648 | 0.78 | PREP (0.56) | PREPLMNAALDH1A1SMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025037000-A1 | NOVEL FIBROBLAST ACTIVATION PROTEIN INHIBITORS AND MEDICAL USES THEREOF | UNIVERSITEIT ANTWERPEN (BE) | 2025-02-20 | — | — | WO | disclosed |