Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | PDE2A | O00408 | 5/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | BRD2 | P25440 | 1/20 | 0.35 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.35 |
| ▸ | PRKDC | P78527 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31385996 | 1.00 | HSP90AA1 (0.38) | HSP90AA1HSP90AB1NPC1KDM4ERAB9A | |
| SCHEMBL31385729 | 1.00 | HSP90AA1 (0.38) | HSP90AA1HSP90AB1NPC1KDM4ERAB9A | |
| SCHEMBL31385947 | 0.88 | CFTR (0.35) | NPC1KDM4ERAB9AMAPTALDH1A1 | |
| SCHEMBL31386061 | 0.88 | CFTR (0.35) | NPC1KDM4ERAB9AMAPTALDH1A1 | |
| SCHEMBL31386133 | 0.88 | CFTR (0.35) | NPC1KDM4ERAB9AMAPTALDH1A1 | |
| SCHEMBL31386255 | 0.87 | PDE10A (0.41) | NPC1KDM4ERAB9AMAPTALDH1A1 | |
| SCHEMBL31386244 | 0.85 | PBRM1 (0.50) | BRD4 | |
| SCHEMBL31385805 | 0.85 | PBRM1 (0.50) | BRD4 | |
| SCHEMBL31386182 | 0.84 | PDE10A (0.37) | NPC1KDM4ERAB9AMAPTALDH1A1 | |
| SCHEMBL31386033 | 0.84 | PDE10A (0.37) | NPC1KDM4ERAB9AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4727591-A1 | SMARCA2 DEGRADERS AND USES THEREOF | Astrazeneca AB (SE) | 2026-04-22 | — | — | EP | disclosed |
| WO-2024256988-A1 | SMARCA2 DEGRADERS AND USES THEREOF | ASTRAZENECA AB (SE) | 2024-12-19 | — | — | WO | disclosed |