Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27037017 | 0.85 | POLB (0.46) | POLBRECQLLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL31387027 | 0.84 | STAT3 (0.36) | POLBRECQLSTAT3CA2CA1 | |
| SCHEMBL31387075 | 0.81 | GRM5 (0.39) | LMNASTAT3GRM5CA2CA1 | |
| SCHEMBL31386901 | 0.81 | HTT (0.52) | POLBLMNAALDH1A1STAT3SMN1; SMN2 | |
| SCHEMBL30955085 | 0.80 | PTGES2 (0.38) | CA2CA1CA9CA12 | |
| SCHEMBL29777577 | 0.78 | POLB (0.50) | POLBRECQLLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL5839859 | 0.78 | POLB (0.50) | POLBRECQLLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL23231156 | 0.78 | POLB (0.50) | POLBRECQLLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL29777583 | 0.78 | POLB (0.50) | POLBRECQLLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL23952507 | 0.78 | POLB (0.50) | POLBRECQLLMNAALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119546576-A | Novel isoquinolinones pyrrolo-pyridones and thieno pyridone sulfonamide derivatives | 豪夫迈·罗氏有限公司 | 2025-02-28 | — | — | CN | claimed |
| CN-119546576-A | Novel isoquinolinones pyrrolo-pyridones and thieno pyridone sulfonamide derivatives | 豪夫迈·罗氏有限公司 | 2025-02-28 | — | — | CN | disclosed |