SCHEMBL313871

SCHEMBL313871

C=CC(=C(C=C)c1ccccc1)c1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKT1 P31749 1/20 0.56
ALDH1A1 P00352 3/20 0.41
TSHR P16473 3/20 0.41
CES1 P23141 3/20 0.41
CES2 O00748 2/20 0.41
DAO P14920 1/20 0.41
NAPRT Q6XQN6 1/20 0.41
CA12 O43570 2/20 0.41
CA1 P00915 2/20 0.41
CA2 P00918 2/20 0.41
CA9 Q16790 2/20 0.41
TDP1 Q9NUW8 3/20 0.40
MAPK1 P28482 2/20 0.40
AKR1C1 Q04828 1/20 0.39
TGM2 P21980 1/20 0.39
CYP3A4 P08684 2/20 0.38
MAPT P10636 2/20 0.38
F2 P00734 1/20 0.38
F10 P00742 1/20 0.38
F12 P00748 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23328518 1.00 AKT1 (0.56) AKT1ALDH1A1TSHRCES1CES2
SCHEMBL5241699 0.87 AKT1 (0.50) AKT1ALDH1A1TSHRCES1CES2
SCHEMBL2574793 0.87 AKT1 (0.50) AKT1ALDH1A1TSHRCES1CES2
SCHEMBL10447304 0.86 AKT1 (0.56) AKT1ALDH1A1TSHRCES1CES2
SCHEMBL14361165 0.85 AKT1 (0.48) AKT1ALDH1A1TSHRCES1CES2
SCHEMBL19959687 0.83 AKT1 (0.46) AKT1ALDH1A1TSHRCES1CES2
SCHEMBL29175028 0.83 AKT1 (0.46) AKT1ALDH1A1TSHRCES1CES2
SCHEMBL3995372 0.81 AKT1 (0.56) AKT1ALDH1A1TSHRCES1CES2
SCHEMBL8089060 0.81 AKT1 (0.56) AKT1ALDH1A1TSHRCES1CES2
SCHEMBL24404592 0.81 AKT1 (0.45) AKT1ALDH1A1TSHRCES1CES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 251 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250052927-A1 UV/HEVL-FILTERING SILICONE HYDROGEL CONTACT LENSES ALCON INC (CH) 2025-02-13 US claimed
WO-2025032504-A2 UV/HEVL-FILTERING SILICONE HYDROGEL CONTACT LENSES ALCON INC. (CH) 2025-02-13 WO claimed
US-11986997-B2 Three-dimensional printing HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2024-05-21 US claimed
EP-3957692-B1 PRIMER COMPOSITION MARABU GMBH & CO KG (DE) 2024-05-15 EP claimed
US-20220088856-A1 THREE-DIMENSIONAL PRINTING HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2022-03-24 US claimed
EP-3957692-A1 PRIMER COMPOSITION Marabu GmbH & Co. KG (DE) 2022-02-23 EP claimed
US-20210402684-A1 THREE-DIMENSIONAL PRINTING HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2021-12-30 US claimed
WO-2020251532-A1 THREE-DIMENSIONAL PRINTING HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2020-12-17 WO claimed
US-10254646-B2 Composition sensitive to radiation in electromagnetic spectrum ranges for printing purposes, printing plate comprising said composition, use of said composition and image development process IBF INDUSTRIA BRASILEIRA DE FILMES S/A (BR) 2019-04-09 US claimed
US-20190015302-A1 FLUORESCENT PARTICULATE MATERIAL L'OREAL (FR) 2019-01-17 US claimed
US-20070221884-A1 Liminescent Silicon Oxide Flakes CIBA SPECIALTY CHEMICALS CORP. 2007-09-27 US claimed
EP-1769049-A2 LUMINESCENT SILICON OXIDE FLAKES Ciba Specialty Chemicals Holding Inc. (CH) 2007-04-04 EP claimed
WO-2006087241-A1 MOULDED OBJECT EXHIBITING A POLYCHROMATIC EFFECT, ASSOCIATED LIGHT DEVICE AND RESIN ARKEMA FRANCE (FR) 2006-08-24 WO claimed
WO-2006008239-A2 LUMINESCENT SILICON OXIDE FLAKES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2006-01-26 WO claimed
EP-1469124-A1 Use of a composition for whitening recycled paper and board pulp De Donato, Fausto (IT) 2004-10-20 EP claimed
EP-0913444-B1 Adhesive compositions VANTICO AG (CH) 2003-07-09 EP claimed
EP-1047729-B1 COMPOSITION FOR BLEACHING MECHANICAL PULP DE DONATO FAUSTO (IT) 2003-01-08 EP claimed
WO-2001010810-A1 A PROCESS FOR THE PREPARATION OF DIVINYL STILBENE COMPOUNDS CIBA SPECIALTY CHEMICALS HOLDING, INC. (CH) 2001-02-15 WO claimed
EP-1047729-A1 COMPOSITION FOR BLEACHING WOODPULP AND PROCESS FOR ITS PRODUCTION De Donato, Fausto (IT) 2000-11-02 EP claimed
WO-1999029779-A1 COMPOSITION FOR BLEACHING WOODPULP AND PROCESS FOR ITS PRODUCTION DONATO FAUSTO DE (IT) 1999-06-17 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190015302-A1 FLUORESCENT PARTICULATE MATERIAL HNRNPM, NPM1, HNRNPF AKT1 4612/4885ALDH1A1 677/4885TSHR 4415/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.