Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WRN | Q14191 | 1/20 | 0.60 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | USP2 | O75604 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31499884 | 0.92 | WRN (0.61) | WRNACHEPOLBL3MBTL1ALDH1A1 | |
| SCHEMBL31499981 | 0.91 | WRN (0.50) | WRN | |
| SCHEMBL31387170 | 0.91 | WRN (0.67) | WRNACHEPOLBL3MBTL1ALDH1A1 | |
| SCHEMBL31499697 | 0.91 | WRN (0.60) | WRNACHEPOLBL3MBTL1ALDH1A1 | |
| SCHEMBL31387143 | 0.90 | WRN (0.70) | WRNACHEPOLBL3MBTL1ALDH1A1 | |
| SCHEMBL25037173 | 0.90 | WRN (0.57) | WRNACHEPOLBL3MBTL1ALDH1A1 | |
| SCHEMBL30038855 | 0.90 | WRN (0.57) | WRNACHEPOLBL3MBTL1ALDH1A1 | |
| SCHEMBL30037352 | 0.89 | WRN (0.74) | WRNACHEPOLBL3MBTL1ALDH1A1 | |
| SCHEMBL25035189 | 0.89 | WRN (0.74) | WRNACHEPOLBL3MBTL1ALDH1A1 | |
| SCHEMBL31499775 | 0.88 | WRN (0.47) | WRNALDH1A1NPSR1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024255765-A1 | NOVEL COMPOUNDS, COMPOSITIONS COMPRISING THE SAME AND USES THEREOF | NUPHASE THERAPEUTICS (HANGZHOU) LIMITED., CO. (CN) | 2024-12-19 | — | — | WO | disclosed |