Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WRN | Q14191 | 1/20 | 0.67 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.30 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.30 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31270575 | 0.93 | WRN (0.77) | WRNACHEALDH1A1MEN1HTT | |
| Hro-761 SCHEMBL30038731 | 0.87 | WRN (0.88) | WRNACHE | |
| SCHEMBL31394201 | 0.87 | WRN (0.64) | WRNACHEALDH1A1MEN1HTT | |
| SCHEMBL25035304 | 0.87 | WRN (0.68) | WRNALDH1A1KMT2ARXFP1TSHR | |
| SCHEMBL30038371 | 0.87 | WRN (0.68) | WRNALDH1A1KMT2ARXFP1TSHR | |
| SCHEMBL31394632 | 0.87 | WRN (0.67) | WRNACHEALDH1A1MEN1HTT | |
| SCHEMBL31387357 | 0.86 | WRN (0.67) | WRNTSHRKDM4EMAPTMAPK8 | |
| SCHEMBL31499664 | 0.86 | WRN (0.77) | WRNACHEALDH1A1MEN1HTT | |
| SCHEMBL31387255 | 0.85 | WRN (0.62) | WRNACHEALDH1A1MEN1HTT | |
| SCHEMBL31387220 | 0.85 | WRN (0.62) | WRNACHEALDH1A1MEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024255765-A1 | NOVEL COMPOUNDS, COMPOSITIONS COMPRISING THE SAME AND USES THEREOF | NUPHASE THERAPEUTICS (HANGZHOU) LIMITED., CO. (CN) | 2024-12-19 | — | — | WO | disclosed |